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Volume 6, Issue 1, Pages 8-9 (January 2010)


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Androgen Reduction Has Few Benefits for SBMA

JEFF EVANS

VITALS

Major Finding: Men with spinal and bulbar muscular atrophy who were treated with dutasteride for 2 years had significantly better physical quality of life, but significantly worse mental quality of life, than did placebo-treated patients. No differences in muscle strength were found.

Data Source: A phase II, randomized, double-blind, placebo-controlled trial of 50 men

Disclosures: The trial was funded by the National Institute of Neurological Diseases and Stroke. None of the investigators had relevant disclosures.

PII: S1553-3212(10)70013-3

doi:10.1016/S1553-3212(10)70013-3


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