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Volume 5, Issue 7, Pages 8-9 (September 2009)


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Valproate Doesn't Delay Psychosis in Alzheimer's

MICHELE G. SULLIVAN

VIENNA — Valproate treatment over 2 years does nothing to delay the onset of agitation or psychosis in patients with Alzheimer's disease, and patients taking the anticonvulsant showed significantly more brain volume loss on MRI at year 1 than did those taking placebo, based on the results of a randomized trial.

PII: S1553-3212(09)70158-X

doi:10.1016/S1553-3212(09)70158-X


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